92. Adult onset chronic recurrent multifocal osteomyelitis (CRMO): experience from Bahrain

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Chronic Recurrent Multifocal Osteomyelitis (CRMO): Presentation, Pathogenesis, and Treatment

PURPOSE OF REVIEW Chronic non-bacterial osteomyelitis (CNO) with its most severe form chronic recurrent multifocal osteomyelitis (CRMO) is an autoinflammatory bone disorder. We summarize the clinical presentation, diagnostic approaches, most recent advances in understanding the pathophysiology, and available treatment options and outcomes in CNO/CRMO. RECENT FINDINGS Though the exact molecula...

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Chronic recurrent multifocal osteomyelitis (CRMO) – advancing the diagnosis

BACKGROUND Chronic recurrent multifocal osteomyelitis (CRMO) is a little known inflammatory bone disease occurring primarily in children and adolescents. Delays in referral and diagnosis may lead to prolonged courses of antibiotics with in-patient care, unnecessary radiation exposure from multiple plain radiographs or bone scans and repeated surgery including bone biopsies. Children (aged < 18 ...

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Recurrent multifocal osteomyelitis (CRMO); effect of neridronate

Introduction Chronic recurrent multifocal osteomyelitis (CRMO) is an autoinflammatory bone disease of unknown etiology. Clinically, the disease is characterized by the insidious onset of local pain and swelling in affected bones. Its course is one of intermittent periods of exacerbation and remission with successive bones affected.CRMO most commonly affects the metaphysis of long bones, especia...

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Chronic recurrent multifocal osteomyelitis (CRMO) in children - single-centre clinical observations and experience.

BACKGROUND CRMO is characterized by chronic bone pain of recurrent nature. The onset is usually at the beginning of the second decade of life. Bony lesions may be visible on radiographs, although sometimes a CT or MRI scan is necessary to visualise them. The aim of study was analyse symptoms, diagnostic difficulties and results of accessory investigations in patients suffering from CRMO. MATE...

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Chronic recurrent multifocal osteomyelitis.

Chronic recurrent multifocal osteomyelitis is an autoinflammatory disorder characterized by bone pain and fever, a course of exacerbations and remissions, and a frequent association with other inflammatory conditions. Because its etiology is largely unknown, the diagnosis is still based on clinical criteria; treatment is empiric and not always successful. The diagnosis is supported by the prese...

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ژورنال

عنوان ژورنال: Rheumatology Advances in Practice

سال: 2018

ISSN: 2514-1775

DOI: 10.1093/rap/rky032